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Spondylarthrite ankylosanteL’Union des consommateurs ne fait aucune recommandation aux personnes qui consomment actuellement Celebrex quant à l’efficacité ou la dangerosité de ce médicament, si ce n’est de consulter leur médecin.Les inhibiteurs sélectifs de la COX-2 réduisent la formation de prostacycline systémique (et par conséquent, possiblement endothéliale), sans altérer le thromboxane plaquettaire.Cependant, chez des sujets sains et dans des études à faible effectif, à doses multiples avec 600 mg deux fois par jour (équivalant au triple de la plus forte posologie recommandée), le célécoxib n'a eu aucun effet sur l'agrégation plaquettaire, ni sur le temps de saignement comparativement au placebo.Si nécessaire, la dose peut être augmentée ultérieurement à 200 mg deux fois par jour.
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Résultats incompletsLe Vioxx et le Celebrex, des médicaments actifs sur les douleurs rhumatologiques, notamment arthritiques, ne font pas l'unanimité: plusieurs études font en effet apparaître qu'ils augmentent légèrement le nombre d'infarctus et d'accidents vasculaires cérébraux.Elle pourrait également jouer un rôle dans la cicatrisation des ulcères.Si vous hésitez sur la conduite à tenir après avoir omis une dose, demandez conseil à votre médecin ou à un pharmacien.L'expérience chez ce type de patients se limite à celle des patients cirrhotiques (voir rubriques Contre-indications, Mises en garde et précautions d'emploi et Propriétés pharmacocinétiques).
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Lorsque j’ai mal à ma hanche, ou mal de dos, je prends des Célébrex , 200 mg.L’organisme de défense des consommateurs reproche au fabricant d’avoir induit les membres du groupe en erreur par une publicité trompeuse, basée notamment sur des informations biaisées.

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